Flexicil: Glucosamine & Chondroiton +

Glucosamine works primarily by supporting the health and function of cartilage, which is the tissue that cushions joints. Here's a closer look at how it functions:

Cartilage Maintenance: Glucosamine is a key component of cartilage, which is made up of proteins and polysaccharides. It helps maintain the structural integrity of cartilage by supporting the production of glycosaminoglycans (GAGs), such as chondroitin sulfate and hyaluronic acid. These GAGs are crucial for the cartilage's resilience and elasticity.*

Joint Lubrication: Glucosamine may also help maintain the synovial fluid in joints. This fluid acts as a lubricant, reducing friction and allowing smooth movement of the joints. By supporting the synthesis of synovial fluid, glucosamine can help reduce joint stiffness and discomfort.*

Anti-Inflammatory Effects: Some research suggests that glucosamine might have mild anti-inflammatory properties. This can help reduce inflammation around the joints, which is often a factor in conditions like osteoarthritis.*

Cartilage Repair: Glucosamine may stimulate the production of chondrocytes, the cells responsible for producing and maintaining cartilage. This could potentially support cartilage repair and regeneration.*

Pain Reduction: By contributing to cartilage health and potentially reducing inflammation, glucosamine might help alleviate joint pain and improve function.*

Chondroitin is another key component of cartilage and is often used in conjunction with glucosamine as a dietary supplement to support joint health. Here's a breakdown of how chondroitin works:

Cartilage Structure: Chondroitin is a major part of the cartilage matrix, where it helps to maintain the structure and integrity of cartilage tissue. It's a type of glycosaminoglycan (GAG), which is a long chain of sugar molecules. These GAGs help attract and retain water in the cartilage, giving it elasticity and cushioning properties.

Water Retention: By attracting and holding water, chondroitin helps keep cartilage hydrated and resilient. This hydration is crucial for maintaining the shock-absorbing properties of cartilage, which helps protect the joints from damage due to impact and pressure.

Cartilage Repair: Chondroitin may promote the synthesis of cartilage components by supporting the activity of chondrocytes, the cells responsible for cartilage maintenance and repair. This can help in the repair of damaged cartilage and in maintaining healthy cartilage levels.*

Anti-Inflammatory Effects: There is some evidence suggesting that chondroitin may have mild anti-inflammatory effects, which can help reduce joint inflammation and associated pain. This can contribute to improved joint function and comfort.*

Inhibition of Cartilage Breakdown: Chondroitin might help inhibit the activity of enzymes that break down cartilage, such as matrix metalloproteinases (MMPs). By limiting cartilage degradation, chondroitin can help preserve cartilage integrity over time.*

Pain Relief and Function Improvement: Some studies indicate that chondroitin supplementation can help alleviate joint pain and improve joint function, especially in conditions like osteoarthritis.*

Overall, while many people find chondroitin helpful for managing joint health, the effectiveness of chondroitin supplements can vary. Source, integrity, and combining with the perfect selection of other ingredients is key.

Methylsulfonylmethane (MSM) is a sulfur-containing compound that's often used as a dietary supplement for joint health and inflammation. Here's a look at how MSM works:

Sulfur Source: MSM is a source of sulfur, which is a vital element for the production of collagen and other connective tissues in the body. Sulfur is important for maintaining the structure and strength of connective tissues, including cartilage, skin, and tendons.

Anti-Inflammatory Effects: MSM has been suggested to have anti-inflammatory properties. It may help reduce inflammation by inhibiting the production of inflammatory molecules like prostaglandins and cytokines. This can contribute to decreased joint pain and swelling.*

Antioxidant Activity: MSM has powerful antioxidant effects, helping to neutralize free radicals in the body. Free radicals can contribute to oxidative stress and inflammation, so reducing their levels can help protect cells and tissues from damage.*

Pain Relief: Some studies suggest that MSM can help reduce pain and improve joint function, potentially due to its effects on inflammation and oxidative stress. It has been said to alleviate symptoms of osteoarthritis and other joint-related conditions.*

Cartilage Health: MSM helps support the health of cartilage by providing sulfur, which is necessary for the synthesis of cartilage components like glucosaminoglycans. This can help maintain cartilage integrity and support joint function.*

Joint Lubrication: By supporting overall joint health and reducing inflammation, MSM may contribute to better joint lubrication and flexibility. This can help improve movement and reduce stiffness.*

Curcugreen® is a branded form of curcumin, which is the active compound found in turmeric. It is specifically designed to improve the bioavailability and effectiveness of Curcumin. Here's how Curcugreenx® works:

1. Enhanced Bioavailability

Improved Absorption: One of the primary challenges with Curcumin is its low bioavailability, meaning it is not easily absorbed by the body. Curcugreen® uses specialized technology to enhance the absorption of Curcumin. This often involves using advanced formulations like phytosome technology, which binds Curcumin to phospholipids, making it more easily absorbed and utilized by the body.

2. Anti-Inflammatory Effects

Inhibition of Inflammatory Pathways: Curcumin, including the Curcugreen® formulation, has been shown to inhibit various inflammatory pathways. It affects key molecules involved in inflammation, such as nuclear factor kappa B (NF-kB) and cyclooxygenase-2 (COX-2). By modulating these pathways, Curcugreen® helps reduce inflammation in the body.*

3. Antioxidant Properties

Neutralizing Free Radicals: Curcumin has strong antioxidant properties. It helps neutralize free radicals, which are unstable molecules that can cause oxidative stress and damage to cells. By reducing oxidative stress, Curcugreen® contributes to overall cellular health and helps protect against chronic diseases.

4. Joint Health

Relief from Joint Pain: Due to its anti-inflammatory properties, Curcugreen® is often used to support joint health and alleviate symptoms of conditions like osteoarthritis. It helps reduce pain, swelling, and stiffness in the joints.*

5. Overall Health Benefits

• Immune Support: Curcumin has been shown to support immune function by modulating immune responses and reducing inflammation.
• Digestive Health: Curcumin may support digestive health by reducing inflammation in the gastrointestinal tract and promoting healthy digestion.

6. Clinical Evidence

Research: Clinical studies have demonstrated that Curcugreen® can be more effective than standard curcumin supplements due to its enhanced bioavailability. Research shows that Curcugreen® can significantly improve symptoms related to inflammation and support overall health.